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424 Cytoplasmic NADH from the glycolytic pathway is delivered to mitochondria through two NADH shuttles, G3P shuttle and MA shuttle, allowing NAD + recycling to sustain glycolytic flux
was the first to suggest that the senescent changes in body composition were causally linked to the concomitant decline in circulation GH and IGF-I levels (24)
432 Other OVs, such as Toca 511 and TG6002, serve as prodrug-converting agents, transforming 5-FC into cytotoxic 5-FU 433 and offering alternative therapeutic options
