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Other groups similarly implicated 4-TBP and 2,4-ditert-butylphenol (2,4-dTBP) in causing depigmentation following occupational exposures 2124 , and three groups reported a variety of systemic abnormalities, including thyroid, liver, and/or splenic changes following exposure

Ethics statement The studies involving humans were approved by Jinhua Central Hospital Medical Ethics Review Committee

Gandhi V, Verma P, Naik G

Based on pharmacokinetic data showing peak plasma concentrations at 30 to 60 minutes and maximal therapeutic effects at 2 to 4 hours, many users find injecting 1 to 2 hours before activity provides optimal results