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doi: 10.1016/j.jsps.2010.07.006

(52) observed in humans that sepsis survivors had lower blood CD4 + and CD8 + lymphocyte counts than non-survivors, suggesting a beneficial effect on health of lower levels of these cell populations during periods of immune challenge

Supplementation with PLP significantly decreased high concentrations of glycation-induced toxic compounds in diabetic rats and prevented the progression of diabetic nephropathy (Higuchi 2006

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