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4a, the Z factor and signal-to-background ratio were 0.70 and 2.60, respectively, indicating that the assay was robust
Addressing its pharmacokinetic limitations and validating its efficacy in humans will be critical steps toward realizing its clinical utility
One of them is the small number of patients, which may lead to false positives, especially as we made no correction for multiple comparisons, given the exploratory nature of this study
It is almost completely avoided with undermethylation and depression
