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There, Drp1 interacts with key adaptor proteins, including mitochondrial fission protein 1 (FIS1), mitochondrial dynamics proteins 49 and 51 kDa (MiD49 and MiD51), and mitochondrial fission factor (MFF), to drive membrane constriction and division (Smirnova et al., 1998
Together, these results suggested that this phenotype could be exploited as cancer therapy through the use of inhibitors of glutaminolytic enzymes or treatment which induce glutamine depletion like L-asparaginase

Drawbacks of Native Strains In this section, native strains represent the organisms in which the natural product is first reported or where the BGCs of interest are first sequenced from

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