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According to a study published in the journal Experimental and Therapeutic Medicine , adults who were diagnosed with metabolic syndromea number of health conditions (such as high blood pressure, high blood sugar levels, high cholesterol and a large waistline) that can raise the risk of heart disease, diabetes and stroke, as defined by the National Institutes of Healthand who initially tested with higher levels of glutathione showed greater reductions in body weight and body fat percentage after following a personalized healthy eating plan for six months

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The first step in the synthesis of GSH is the formation of -glutamyl-cysteine (GluCys) from the constituent amino acids glutamate and cysteine by the enzyme -glutamyl-cysteine synthetase (GCS, also called glutamate cysteine ligase (GCL))

A 2014 study in Oxidative Medicine and Cellular Longevity highlighted Glutathiones role in neutralizing free radicals and protecting cells from oxidative stress (Polonikov, 2014)