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In animal studies, AOD-9604 treatment reduced body weight gain by over 50% compared to controls over a 19-day period, with increased lipolytic activity in adipose tissue
doi: 10.1126/science.1256271 21 Levin-KleinRBergmanY
A recent finding shows that cells lacking ATAD1, an AAA + ATPase that removes substrate proteins directly from the OMM for degradation, are hypersensitive to proteasomal inhibition (Winter et al., 2022)
[DOI] [PubMed] [Google Scholar] 11.van der Heide A, Donjacour CEHM, Pijl H, et al
