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175 The mechanism by which GLP-1R agonists promote beneficial cardiovascular outcomes is multifactorial

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When combined with hyaluronic acid, effects were even more pronounced, with animals showing better cartilage structure preservation and shorter periods of lameness

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Increased oligomerization and phosphorylation of alpha-synuclein are associated with decreased activity of glucocerebrosidase and protein phosphatase 2A in aging monkey brains

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To understand the underlying mechanisms, inhibitors targeting the Notch pathway (DAPT) and NF-B pathway (BMS) were also applied to HUVEC and murine CLI models

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