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Cardiovascular diseases are a leading cause of mortality worldwide, and managing risk factors such as high blood pressure, cholesterol, and oxidative stress is vital

Databases searched (and their content coverage dates) were Ovid MEDLINE(R) (1946+ including epub ahead of print, in-process, and other nonindexed citations), Ovid Embase (1974+), Ovid APA PsycInfo (1967+), Ovid Cochrane Central Register of Controlled Trials (1991+), Ovid Cochrane Database of Systematic Reviews (2005+), Web of Science Core Collection via Clarivate Analytics (1975+), and Scopus via Elsevier (1974+)

In another study, 209 patients with chronic viral hepatitis were investigated, of which 85 patients had splenomegaly and 124 had a normal spleen size

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