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[PMID: 23370917 DOI: 10.1164/rccm.201211-1981OC] [DOI] [PubMed] [Google Scholar] 22.J.D

Redox Signal 16, 476495

Here, we provide the first evidence of improved healthspan and age-related survival with a therapeutic mAb by demonstrating that treatment with an IGF-1R antagonist in older mice significantly and preferentially improves several indices of healthspan, reduced death from neoplastic disease, and increased mean and median lifespan in females

It is an emollient and skin conditioning agent that is able to integrate seamlessly into the skin's lipid barrier without clogging pores