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Abnormal distribution, excess, or deficiency of Cu can trigger and accelerate the progression of diabetes mellitus (DM) and its complications through redox imbalance and activation of inflammatory pathways

Efficacy of intravenous glutathione vs

Moreover, NO seems to be the only mediator of cell proliferation arrest through the ERK1/2-p53 signaling pathway ( FIGURE 1 Next to this evidence, in our laboratory it has been demonstrated that GSH depletion modulates the peroxisome proliferator-activated receptor gamma, co-activator 1 alpha (PGC-1) expression and its downstream metabolic pathway in neuronal and skeletal muscle cells ( Figure 1 )

Discussion In the last decade many efforts were employed in research and development of new pharmacological treatments of FXS and simultaneously great advances were made in developing peptides therapeutics against several diseases