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The physiological properties of vascular, renal, and heart EET increase blood flow, induce vasodilation, inhibit platelets, promote angiogenesis and the hyperpolarization of vascular smooth muscles, inhibit apoptosis, inhibit fibrosis and exert powerful anti-inflammatory effects ( 4 AA metabolites in AKI In this section, we discuss the role of certain AA metabolites generated by COX, LOX and CYP450 in the development and progression of AKI (Table 1)

doi: 10.1089/ars.2021.0096 33 Bilska-WilkoszAIciekM

By adjusting key parameters, PCA can simplify the molecular motion to provide insights into essential biological processes, for example, protein folding and the opening and closing of ion channels 89,90

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