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Biomarkers of cobalamin (vitamin B-12) status in the epidemiologic setting: a critical overview of context, applications, and performance characteristics of cobalamin, methylmalonic acid, and holotranscobalamin II

One of the most challenging limitations includes the ability to identify whether treatment for IDA is effective because the average lifespan of an erythrocyte is approximately 120 days, 21 and typical preoperative lab workup is conducted with a shorter duration to surgery than that

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For achieving pharmacological effects under investigation for cancer or critical care applications, injections represent the only viable delivery method