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A double-blind randomized trial with placebo and oral glutamine has shown that glutamine reduces changes in intestinal absorption and permeability (assessed by d-xylose urinary excretion and cellobiose-mannitol test, respectively) induced by FU and may have a protective effect on the FU-induced diarrhea.[80] Although there is no evidence of a beneficial effect of glutamine during pelvic radiotherapy-induced diarrhea for colonic carcinoma[81] a beneficial effect of oral glutamine for FU-induced diarrhea in colonic carcinoma is supported.[82] Even mild diarrhea must not be discounted when evaluating the effect of chemotherapy-induced diarrhea

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Rather than simply masking symptoms, the peptide works to enhance the bodys natural repair mechanisms, making it an appealing option for those seeking a more proactive and regenerative approach to health

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