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doi: 10.1128/microbiolspec.TBS-0010-2012
This is in concordance with past evidence noting significant degradation of full-length tubulin- with increased post-mortem interval in human brain, as well as similar findings noted in other biological samples such as bone and skeletal muscle 37,38
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In fat cells, 5-amino-1MQ lowered the NNMT byproduct 1-methylnicotinamide (EC50 near 2.3 micromolar) and cut fat storage, without disturbing the other enzymes in the NAD+ salvage pathway
