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Tissue analysis revealed an absence of neuroendocrine cells and an abundance of T-cells in tumors treated with VHH1-28BBz-CDH17-CAR-T cells, indicating rapid tumor elimination ( Chimeric Therapeutics, an Australian leader in cell therapy, announced on October 31, 2023, that the FDA had approved the Investigational New Drug (IND) application for CHM 2101 (CDH17-CAR-T), paving the way for further trials
Lancet 2021;398:80316
