glutathione peroxidasecatalse peroxidase Glutathione Peroxidase - Proteases -

doi: 10.1038/s41418-020-0528-x 111 FangYChenXTanQZhouHXuJGuQ

Such drugs function as inhibitors, binding to the active site by mimicking the tetrahedral intermediate of its substrate, thus disabling the enzyme

10 Defined as attaining a medically stable, steady state in which the patient is adequately supported to prevent deterioration of their illness

Ferroptosis suppressor protein 1 (FSP1, also known as flavoprotein apoptosis-inducing factor mitochondria-associated 2, AIFM2) protects cells against ferroptosis regardless of the cell GSH level, GPX4 activity level, or p53 status, and its activity is mediated by extramitochondrial ubiquinone (also known as coenzyme Q10, CoQ10) [6]