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The hypothesis is that by combining these two agents, one addresses the systemic hormonal signals that govern eating behavior and macroscopic energy balance, while the other fine- tunes the cellular machinery responsible for metabolic efficiency

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This finding warrants further investigation to determine whether peripheral expression of this transporter could serve as a useful biomarker for neurodegenerative diseases

The enhanced cocktails, CILy (CHIR+IDE1+Ly) and CIP (CHIR+IDE1+PD), significantly increased the expression of DE markers SOX17 and FOXA2, with CIP showing the highest efficiency, comparable to the traditional CA method