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Schreurs M, Kuipers F, van der Leij FR
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Kelly A B, Timothy D M, Frank E M, Tegan E H

The combination of RT with ferroptosis inducers such as RSL3 or Erastin further intensifies lipid peroxidation and increases radiosensitivity, a synergy that has been confirmed in various cancer models (38)

As a consequence of the inhibition of G6PDH, tumor cells are less able to produce the NADPH necessary to handle the increased oxidative stress of the tumor microenvironment
