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Involvement of the SIRT1-NLRP3 pathway in the inflammatory response

In summary, these results emphasize the important role of oxidative stress in epileptogenesis and related neuropathology

Activated IGF-1R is commonly present at focal adhesions, where it can form a ternary complex containing integrin/IGF-1/IGF-1R and protect -integrin from proteasomal or lysosomal degradation, thereby affecting the expression of -integrin and inhibiting cell adhesion to the basement membrane in tumors [50,51]
L., Lacy D
