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Duarte, J

Moreover, it was pointed out that gliflozin-induced infection, cancers, liver injury, hypoglycemia, and hypovolemia dehydration, hypovolemia, but mostly hypotension or orthostatic hypotension, and hemoconcentration (and thereby, the risk for thrombosis) affected bone metabolism and increased the risk of fracture [42,43,44]

This metabolic imbalance occurs several times a day, whenever food is ingested, and at this time there is a great opportunity for cell injury, which, with the aging of the biological defense and repair systems, ends up manifesting in cell dysfunction and disease [19]