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Grape seed proanthocyanidins (GSPAs) also showed protective role against AFB1-induced DNA damage

GSH, containing a thiol group derived from cysteine, serves as a vital antioxidant, neutralizing ROS and reactive nitrogen species, maintaining cellular redox balance and detoxifying xenobiotics (89)

It is thought that 5hmC is particularly crucial in the brain due to its high abundance there compared to other organs (Li and Liu, There is substantial evidence to suggest that DNA methylation is critically affected by sleep

As such, the soluble form of the chemokine acts in a paracrine fashion on microglia and neurons, as well as a chemotactic agent for infiltrating immune cells (Imai et al., 1997