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Third, serine and arginine levels were lower in HFpEF than in HFrEF, reflecting endothelial dysfunction in HFpEF.160 Proteomics Exploration of 92 proteins from the Olink cardiovascular II panel and their association with obese HFpEF has been recently reported in the LIFE-Heart study (999 patients with HFpEF and 999 patients without HF)

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To assess the robustness of findings, statistical power was estimated using the pwr package in R (version 4.4.1)
