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Nat Commun (2022) 13(1):2801

Their brains are still developing, making them more vulnerable to injury and often slower to recover

Amino acid metabolism, particularly the glutamine-glutamate cycle, is also impacted, with GLS upregulation supporting the TCA cycle and nucleotide synthesis
They were found to have significant HbA1c, and weight reduction compared to placebo in patients with diabetes and obesity respectively
