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Food and Nutrition Board recommends a safe upper limit of 100 mg per day, rare cases of pyridoxine-induced peripheral neuropathy have been reported in people taking doses as low as 2440 mg per day, indicating important differences in individuals metabolism of pyridoxine
10.1371/journal.pmed.1002265 253 SchneiderA.Schulz-SchaefferW.HartmannT.SchulzJ

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