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GHK-Cu is a copper tripeptide found naturally in human plasma

Although the magnitude losses of folate content of raw materials (wheat flour, wheat bran, dough, bakers yeast, and vegetables) due to the heat treatment during breadmaking were about 45%, the fortification increased the total folate content by up to 190% and 100% in white and whole-grain bread, resp., without adverse effects on sensory properties, such as odour and taste, or overall consumer acceptance of the vegetable-fortified bread 432

Based on these findings, it can be concluded that the early studies using PCPA likely produced misleading results regarding the role of serotonin in sleep due to the confounding factor of hypothermia