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Comprehensive proteomic analyses have already identified hundreds of proteins in citrus-derived EVs [22], including metabolic enzymes and signaling-related proteins, revealing that these vesicles carry a diverse array of enzymes and signaling proteins capable of modulating host physiology

These compounds are rich in polyphenolic profile which help in reduction or elimination of free radicals thus produced at least some positive results against fluoride toxicity
Engineering the nanoparticle-protein interface: applications and possibilities

Settembre, C
