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It facilitates the transportation of fatty acids into the mitochondria, where they are converted into usable energy
Loop diuretics cause less postural hypotension than thiazide diuretics in the frail elderly
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The consumption of free l-carnitine and free CoA due to the accumulation of long chain acyl groups can limit acetyl-l-carnitine synthesis, since free l-carnitine levels are critical for maintaining the buffering capacity of CPTs
