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However, preterm neonates often have deficient Zn levels and subsequent reduced SOD activity
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A recent investigation identified that several crucial cuproptosis-related genes (CRGs), such as ATP7A, CP, copper-dependent lysyl oxidase-like 2 (Loxl2), and Phosphodiesterase 3B (PDE3B), exhibit upregulation in neurons following SCI, thereby initiating cuproptosis and neuroinflammation at the central lesion sites
