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Therefore, bi-directional causal effects were observed, and instances of true bi-directional pathway might exist, and in other words, a proposed positive effect of vitamin B12 on NAFLD risk, whereas NAFLD also exerts a positive effect on vitamin B12, possibly as part of a positive feedback loop

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They slow gastric emptying, increase satiety, act on appetite signaling in the brain, and enhance glucose-dependent insulin secretion

An over-the-counter pill has to survive digestion, and the body absorbs only a small fraction of it