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ROS also promotes the expression and activation of MMPs, particularly MMP-9, which degrade occludin and claudin, widening intercellular gaps between endothelial cells (Figure 3) [160,169]
KEY POINTS Reactive Oxygen Species (ROS) are highly reactive substances derived from oxygen that are capable of damaging DNA, lipids and proteins
Glass showed pH 8.368.62 and BA 10.9514.03 mg/mL
