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Low B12 levels can lead to megaloblastic anemia, a condition where red blood cells are abnormally large and unable to transport oxygen efficiently, causing symptoms like fatigue, weakness, and breathlessness
Human studies are the most effective way to assess nanomaterial toxicity through multiorgan/system analyses, but they face cost and risk barriers that limit direct exposure data

ACS Synth Biol 4:723728
Interactions Between Endocannabinoid and Serotonergic Systems in Mood Disorders Caused by Nicotine Withdrawal
