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The optimal ratio of SMNB /HCQ for synergistic anti-tumor cells in hypoxia In combinatorial therapy, HCQ functions as a mitochondrial autophagy inhibitor, whereas SMNB serves as both a mitochondrial disruptor and a mitophagy inducer, allowing for the spatiotemporal regulation of mitophagy
Decreased pigmentation (light blue & clear in image) in c indicates increased ABTS radical scavenging activity
10.1016/j.brainresbull.2024.111024 51
