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They also noted significant upregulation of an oxysterol-binding protein that may play a role in intracellular hydrocarbon transport (Fukuda, 2023)
For example, in HCC mouse models, stigmasterol remodels gut microbiota, increases Lactobacillus abundance, leads to a decrease in the proportion of regulatory T cells (Tregs) in the tumor microenvironment, and simultaneously increases the proportion of IFN- + CD8 + T cells with killing function, thereby enhancing antitumor immunity
This is where personalized care and choosing the right treatment play a significant role
Biochem Pharmacol (2013) 85(7):97790
