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[66,67] During melanogenesis, tyrosinase is responsible for the conversion of L-tyrosine to L-DOPA and subsequently to dopa-quinone, then the pathway bifurcates to produce eumelanin or phaeomelanin
Additionally, metabolomics technology should be used to monitor changes in energy metabolism, providing a comprehensive assessment of their therapeutic potential

Absorbance was measured at 450 nm (reference = 650 nm) using a microplate reader
