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Given a reduction in both GPx3 and a likely reduction of glutathione production, as has been theorized by others in the field of konzo 13 , the role of oxidative damage and mitigation as a contributing factor of disease susceptibility or severity is only further bolstered by the findings of this study

Mutations in the P53 gene and expression of tumor protein 53 (TP53) have been observed in more than 50% of cancer types

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This may theoretically offer a more sustained window of availability to tissues like the liver and kidney that can actually utilize circulating glutathione