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President Biden signed the FDA Modernization Act 2.0 into law, with strong bipartisan support, to speed up the discovery process, lower the costs of new life-saving treatments, and reduce animal testing (217)

Recently, a GLS1 selective inhibitor, CB-839 (telaglenastat), tested in preclinical trials showed no significant side effects and, therefore, was moved forward into clinical trials

doi: 10.1016/j.exger.2004.10.004

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