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[DOI] [PubMed] [Google Scholar] 113.Minshew N, Goldstein G, Dombrowski SM, Panchalingam K, Pettegrew JW

Moreover, amino acid deficiency can also initiate the transcription of autophagy genes such as Atg12, Atg5, Atg7, and Beclin-1 through the activation of the GCN2/eIF2/ATF4 pathway, triggering the autophagy process and increasing the amino acid content in the cytoplasm [79]

An alternative is to develop substances that are safer for the epithelial barrier and are substitutes for commonly used, dangerous compounds [1]
