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For the gut microbiota hypothesis, broad-spectrum antibiotics could be employed to deplete the microbiota to verify therapeutic dependency, while fecal microbiota transplantation (FMT) experiments could confirm the sufficiency of the microbiota as a mediator

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Kim specifically recommends Matrixyl 3000 as "it is a great peptide blend of Palmitoyl Tripeptide-1 + Palmitoyl Tetrapeptide-7 which work synergistically to stimulate collagen production and reduce inflammation." Leave-on products: Wnek suggests sticking with products that stay on the skin instead of rinse-off products so that they have enough contact time with skin for optimal benefits

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