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The better effect of LCLN than LC was evidenced by the findings of earlier studies 92,100 , likely due to physical attributes (including shape, size, and zeta potential), alongside enhancements in encapsulation efficiency, drug content, drug loading capacity, drug release, and in vitro release of the formulated LC-SLNs, all of which were optimized in the niosomal form 19

34 In the mitochondria, it is involved in numerous bioenergetic reactions, including a critical step bridging glycolysis and the citric acid cycle

Joo Roberto Resende Fernandes (CRM-SP 203006/RQE 91325), mdico do Pronto Atendimento e Corpo Clnico, especialista em Clnica Mdica do Hospital Israelita Albert Einstein