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Description
The replacement of 17 followed by oxidation gave rise to ALA

Wolfe et al., 2023)

Regulation of other signaling pathways In addition to Nrf2 and insulin signaling pathways, lipoic acid was found to target other cell-signaling molecules thereby affecting a variety of cellular processes, including metabolism, stress responses, proliferation, and survival

It also has a layer of muscle close to the surface which promotes absorption of B12
