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PI3K then produce phosphatidylinositol (3,4,5)-trisphosphate (PIP3), which recruits and activates Akt (protein kinase B)
Health Promotion Administration, Annual report of cancer statistics in Taiwan in 2021

[DOI] [PMC free article] [PubMed] [Google Scholar] 251.Shao Y., Gu W., Jiang L., Zhu Y., Gong A

Misfolded syn, a presynaptic neuronal protein, forms soluble oligomers and insoluble fibrils that overwhelm cellular proteostasis mechanisms, leading to progressive intraneuronal accumulation [9, 10]
