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Side effects of Topical GHK-Cu have not been widely reported and it is considered generally safe, particularly at typical cosmetic usage concentrations

Autophagy is initiated by the autophagy-activating protein complex that includes the UNC-51-like kinase (ULK1), autophagy-related protein 13L (ATG13L), family interacting protein of 200 kDa (FIP200), and ATG101 [254]