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Antioxidant activity According to Hsu et al

Another judging factor for the availability and biosynthesis of GSH is the Nuclear factor erythroid 2-related factor 2 (NrF2) which is the major transcriptional factor that governs the expression of GSH and its related transporters among multiple anti-oxidant cellular responses [55, 56]

In SK-N-BE cells, etorphine-induced hDOR desensitization is totally inhibited by using the dominant negative GRK2 mutant K220R but is only reduced when using PKC and tyrosine kinase inhibitors (Marie et al., 2001)

Similarly, it does not exhibit features of traditional apoptosis, including cell shrinkage, chromatin condensation, apoptotic body formation, and cytoskeletal disintegration