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Cognitive decline in different treatment groups Statin users compared to non- users of statins Statin use was associated with a slower cognitive decline over time compared to no use of statins

Podiatrists widely use PRP for the treatment of plantar fasciitis, Achilles tendon, and ankle ligament injuries

Pattern HED extrapolation ceiling Daily Dose ~650 mg/day Tablet Math (50 mg) 13 tablets/day included only to show the gap with vendor doses Frequency n/a Notes Allometric scaling from 100 mg/kg/day mouse dose to 80 kg human

An important anti-apoptotic pathway that that allows senescent cell survival involves expression of members of the BCL-2 family of proteins, including BCL-2, BCL-XL, and BCL-W (60)
