cellular glutathione peroxidase deficiency and endothelial dysfunction Lack of peroxidase-1 facilitates a pro-inflammatory activated vascular endothelium Frontiers | Research progress of
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For instance, a bioresponsive group with a pKa close to 6.5 is more likely to be activated in the mildly acidic TME, whereas a lower pKa may result in activation within lysosomes
Vujic et al
A mathematical model of glutathione metabolism
C., et al
