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This exemplifies a typical role of GTP in biologyas a timer of switches and as an informational molecule
The bioavailability difference between routes means the same biological effect requires a higher oral dose than injectable but the mechanistic effects themselves translate across routes because the absorbed fraction reaches systemic circulation intact enough to engage the same downstream pathways
Garaycoechea, J
To investigate whether VRK2 directly phosphorylates Sec24C, we carried out an in vitro kinase assay and found that overexpression of VRK2 was able to increase the phosphorylation level of Sec24C
