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Chemical Reaction : The toxicant reacts with the active components of the catalyst to produce inactive compounds that cover the catalyst surface

This inflammatory process is characterized by the activation of resident glial cells, the release of proinflammatory cytokines and chemokines, and the recruitment and infiltration of peripheral cells into the CNS as a consequence of the breakdown of the blood-brain barrier (Kelly et al., 2020)

10.1021/cr9002193

The accompanying extracellular flow of water convects nutrients towards the deeper lying fiber cells, while the outward intercellular flow, driven by a hydrostatic pressure gradient [99], removes wastes and creates a well-stirred intracellular compartment (Figure 3B, bottom panel )