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Description
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This study employed a comprehensive proteomic and metabolomic analysis to characterize adaptive cellular mechanisms of priority pathogensEscherichia coli, Klebsiella pneumoniae, Enterococcus faecium, and Staphylococcus aureusunder sub-inhibitory concentrations of antibiotics
Metronidazole targets stress responses in Helicobacter pylori, and ether analogues showed enhanced antibacterial potency and favourable pharmacology and achieved bacterial eradication in a mouse model.
