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Likewise, knockout or knockdown of FATP5 in mice reduces hepatocyte fatty acid uptake, hepatic triglyceride content, and reverses steatosis [16, 17] indicating a role of FATP-mediated lipid uptake as a facilitator of hepatic steatosis
Humans have six ALOX genes, including ALOX5, ALOX12, ALOX12B, ALOX15, ALOX15B, and ALOXE3, which influence ferroptosis in different ways depending on the situation (64)
These pathological results were the primary motivation behind the selection of the NaOH alkali burn model to estimate the effects of PYC on CWH
